ABSTRACT
The oral cavity is an attractive site for drug delivery. It offers the advantages of ease of administration, patient acceptability, ease of removal, and termination of dosage at will, among others. In addition, it lends itself to a range of simple delivery systems ranging from solution and tablets to the more complex patch formulations. This chapter describes the background theory and rationale for developing polysaccharide-based mucoadhesive buccal tablets for protein delivery and describes the research that has been conducted on this technology.
