ABSTRACT

Adverse side effects, drug metabolism by first-pass effect in the liver, poor patient compliance, or rejection of an invasive medication often hampers the success and efficacy of therapeutic treatment. Many scientists have tried to overcome these hurdles by designing better and safer drug delivery strategies. In the early 1980s, liposomes were among the most promising drug carriers [1], with high hopes also being put in dendrimers [2] and other complex polymer systems.