ABSTRACT

I. INTRODUCTION A. Intraject Intraject is a prefilled, disposable device for the needlefree subcutaneous injection of liquid drugs and vaccines (Fig. 1). Intraject is greatly preferred by patients to needle and syringe injection, and is replacing both prefilled syringes and autoinjectors in many commercial product areas. The list of these product areas and the companies licensing Intraject (Table 1) reflects the growing demand for this technology. This demand is fueled by a growing concern over the extent and risk of needlestick injuries, the highly competitive and genomics-driven biotechnology pipeline that is increasingly developing injectable drugs, and a trend toward long-term administration of these drugs in the home setting.