ABSTRACT

The interrelationship of sepsis and acute lung injury is complex. The development of signs of systemic inflammation due to infection, sepsis, is the most common cause of acute lung injury (ALI) accounting for 40-50% of all cases (1, 2). The subset of ALI victims with the most severe oxygenation abnormalities are said to have acute respiratory distress syndrome (ARDS). A reciprocal relationship exists in that the lung is the most commonly identified site of infection leading to the development of sepsis (3).