ABSTRACT
APME is the most common CNS complication and occurs in about 0.1% of natural measles infections [3]. Its mortality ranges between 10% and 40%, and most of the survivors are left with long-term sequelae. SSPE and MIBE are rare complications but are almost always fatal. Currently, neither acute measles nor its neurological complications are susceptible to any specific therapy. Treatment is primarily symptomatic, and its effectiveness is only palliative if that. Prevention of the primary disease through vaccination is the only effective means of preventing its severe neurological complications.
