ABSTRACT
The dawn of modern antibacterial chemotherapy began in the 1930s when Germany’s Gerhard Domagk identified sulfonamides as chemotherapeutic agents, for which he was awarded the Nobel prize in medicine in 1938 [1]. The development of penicillin G, by England’s Sir William Dunn and Australia’s Howard Florey, followed during the early 1940s [2]. Tetracycline (chlortetracycline, 1948), aminoglycoside (streptomycin, 1949), macrolide (erythromy-
cin, 1952), and glycopeptide (vancomycin, 1956) antibacterial classes were introduced during the decade that followed the end of World War II [3].
