ABSTRACT

ABSTRACT: Objective: To evaluate the safety and efficacy of pemetrexed and carboplatin chemotherapy combined with whole brain radiation therapy for non-small cell lung cancer with brain metastasis.

Methods: A retrospective analysis of 45 cases of non-small cell lung cancer with brain metastasis treated with combined pemetrexed and carboplatin chemotherapy plus whole brain radiotherapy. The primary endpoints were disease progression and the completion of chemotherapy given after whole brain radiotherapy.