ABSTRACT
Coronary Heart Disease (CHD), which is closely related to disorder of blood lipid metabolism, is the most common chronic complication in patients with diabetes mellitus (DM). Abnormality of lipid metabolism would result in the process of atherosclerosis (AS) and CHD in patients with DM (Smaoui et al 2004, Murase et al 2008). HDL-C would give a great contribution to prevent from the pathogenesis of AS (Goldbourt et al 1997). Some studies further manifest that there is a close contact between the ratio of low-density lipoprotein cholesterol (LDL-C)/ high-density lipoprotein cholesterol (HDL-C) and CHD pathogenesis (Manninen et al 1992, Kannel 2005, Mohan 2005). Scholars believe that the ratio of LDL-C/HDL-C is a more available clinical marker for determining risk of pathogenesis of cardiovascular disease (Packard et al 2005, Fernandez et al 2008).
