ABSTRACT

ABSTRACT: Objective: The purpose of this study was to describe changes in serum lipid following a high-fat dietary and Diet Restriction (DR) intervention plus swimming training. Methods: Eight-week-old female Wistar rats were randomly divided into 5 groups: normal control group, high-fat diet group, high-fat diet and 60 minutes of swimming exercise group, 30% high-fat diet restriction, 30% high-fat diet restriction and 60 minutes of swimming exercise group. After 12 weeks, levels of serum cholesterol were measured in rats. Results: When compared with the NC group, the TC and LDL increased in HFD group, TG decreased and the HDL increased in HFD-S group. Compared to HFD group and HFD-S group had higher HDL. TC, TG and LDL in 30% HFD-S group were significant lower than 30% HFD group. Conclusions: DR alone could reduce hyperlipidemia of HFD animals, and swimming exercise could induce elevated HDL. Additionally, DR plus swimming exercise intervention could decrease TC, TG, LDL, and increase HDL.