ABSTRACT
Patients’ compliance with medical treatment regimens is far from complete. This is true for medicine in general1, for treatment of most psychiatric disorders2 and for lithium treatment of bipolar disorder patients in particular3. Jamison, in her pioneering research into the subject of compliance with long-term lithium treatment, reviewed comprehensively the state of the art in 1990 in her textbook on manicdepressive illness3. This chapter offers brief summaries of the position in 1990 and reviews significant contributions to the knowledge of compliance with lithium acquired during the following 15 years.
