ABSTRACT
This chapter considers the pharmacological and toxicological responses of the organism to the modern-day riot control agents (RCA) o-chlorobenzylidene malononitrile (CS), dibenz[b,f ]1:4-oxazepine (CR), and chloroacetophenone (CN). The animal pharmacology/toxicology of modern riot control agents (RCAs) CS, CR, and CN are presented – and in some instances reference to the human toxicology of RCAs is made to address the comparative toxicological aspects. This discussion is augmented by also addressing the toxicology of RCA formulations, the toxicology of degradation and decontamination products as well as an abbreviated overview of the toxicology of carriers/solvents and propellants used in RCA formulations. The pharmacology and toxicology of oleoresin capsicum (OC) and capsaicinoids are covered in Chapter 7, and a detailed account of the human pharmacology/toxicology of CS, CR, and CN is presented in Chapter 11 by Stopford and Sidell.
