Introduction to Systems Biology for Mathematical Programmers
Abstract Many recent advances in biology, medicine, and health care are due to computational efforts that rely on new mathematical results. These mathematical tools lie in discrete mathematics, statistics and probability, and optimization, and when combined with savvy computational tools and an understanding of cellular biology, they are capable of remarkable results. One of the most signiﬁcant areas of growth is in the ﬁeld of systems biology, where we are using detailed biological information to construct models that describe larger entities. This chapter is designed to be an introduction to systems biology for individuals in operations research (OR) and mathematical programming who already know the supporting mathematics but are unaware of current research in this ﬁeld.