ABSTRACT

Familial investigation features prominently in forensic science within both the criminal and civil jurisdictions.558,772 This chapter reviews the application of autosomal STR evidence to parentage testing and discusses the issues associated with mutation, null alleles, and genetic anomalies. Use of single-locus probe data or multilocus probe data follows similar principles.269 Application of both X-and Y-linked markers750 to these purposes is also briefly reviewed. This chapter concentrates on pedigrees involving one or two alleged parents and one or more children. In a later chapter we will consider the application of familial testing to more complex pedigrees.