ABSTRACT
Due to often limited sample size, it is an absolute ‘must’ not to waste sample material by preparing it before the HPLC method is considered suitable for use. Problems encountered at this stage may take some time to diagnose and repair (see Chapter 10) and samples can and do degrade with time (see Chapter 6). System suitability parameters can usually be defined in two ways: the system performance and the chromatographic suitability.
