ABSTRACT

There are a number of different approaches for the isolation of genomic DNA. Each procedure begins with some form of cellular lysis, followed by deproteinization and recovery of DNA. The main differences between the various approaches lie in the extent of deproteinization and the size of the DNA isolated. In addition, the isolation or extraction of DNA will vary according to the type of biological sample, the amount of evidence or biological sample, and the type of cell(s) present in the sample.