ABSTRACT

Beck Depression Inventory [BDI], Patient Health Questionnaire-9 [PHQ-9]), or target symptoms

– Education and advice about daily activities, identifying and avoiding or resolving stressors, tackling maladaptive behaviours such as alcohol or substance use, healthy diet, exercise

– Low-or high-intensity psychological treatments – Community nurse, support worker or social worker input

■ It is not possible to predict at what dose an individual patient will respond, and many modern drugs do not have a clear dose-response efficacy within their licensed doses (e.g. SSRIs).