ABSTRACT

A First Course in Systems Biology is a textbook designed for advanced undergraduate and graduate students. Its main focus is the development of computational models and their applications to diverse biological systems. Because the biological sciences have become so complex that no individual can acquire complete knowledge in any given area of

1: Biological Systems2: Introduction to Mathematical Modeling3: Static Network Models4: The Mathematics of Biological Systems5: Parameter Estimation6: Gene Systems7: Protein Systems8: Metabolic Systems 9: Signaling Systems10: Population Systems11: Integrative Analysis of Genome, Protein, and Metabolite Data12: Physiological Modeling: the Heart as Example13: Systems Biology in Medicine and Drug Development14: Design of Biological Systems15: Emerging Topics in Systems Biology