ABSTRACT
Published in 1980: In a previous publication on glucuronic acid both free and conjugated, the author expressed the hope that glucuronic acid studies over the following few years might expand vigorously. The have expanded, and none more vigorously that the study of biosynthesis of simple glucuronides.
TABLE OF CONTENTS
part I|2 pages
Glucuronidation, Glucuronides, and Studies on UDPGlucuronyltransferase In Vitro
chapter Chapter 1|16 pages
Introduction — The Biological Function of Glucuronidation
chapter Chapter 2|16 pages
Structure and Properties of Glucuronides
chapter Chapter 3|16 pages
Mechanism of Glucuronidation
chapter Chapter 4|16 pages
Location of Udpglucuronyltransferase in the Cell
chapter Chapter 5|16 pages
Factors Affecting Udpglucuronyltransferase Activity In Vitro
chapter Chapter 6|16 pages
Purification of Udpglucuronyltransferase and its Heterogeneity
chapter Chapter 7|16 pages
Acceptor Substrates of Udpglucuronyltransferase and their Assay
chapter Chapter 8|16 pages
Enzymic Mechanism of Glucuronyl Transference by Udpglucuronyltransferase
chapter Chapter 9|16 pages
Metabolic Pathways Immediately Preceding and Succeeding Glucuronidation — Anabolic Pathways
part II|2 pages
Factors Affecting Glucuronidation In Vivo
chapter Chapter 10|16 pages
The Effect of Age on Glucuronidation
chapter Chapter 11|16 pages
The Influence of Diet on Glucuronidation
chapter Chapter 12|16 pages
The Influence of Sex, Species, and Strain on Glucuronidation
chapter Chapter 13|16 pages
The Influence of Hormones and Xenobiotics on Glucuronidation
chapter Chapter 14|16 pages
Extrahepatic Glucuronidation
chapter Chapter 15|16 pages
Glucuronidation in Cultured Tissue and in Pathological and Toxicological Conditions
chapter Chapter 16|16 pages
Relation of Other Drug-Metabolizing Pathways to Glucuronidation
part III|2 pages
Practical Aspects