ABSTRACT
Lung biopsy specimens show diffuse interstitial fibrosis in the alveolar septae and peribronchial fibrosis. Patients who have pulmonary fibrosis must be carefully monitored for the occurrence of viral, bacterial, or mycoplasmal infections and aggressively treated accordingly. The frequency of the disease and the lack of neurological involvement in the adult form of Gaucher disease is particularly worthy of research efforts to develop enzyme replacement therapy. Certain persons with cystic fibrosis may present with mild pulmonary involvement characterized radiographically by mild interstitial pattern unrelated to the presence of respiratory infection. Interstitial pneumonia with mononuclear cells is common in postmortem studies of lungs from persons with cystic fibrosis (CF). Interstitial pneumonia with mononuclear cells is common in postmortem studies of lungs from persons with CF. The prevalence of allergic rhinitis, atopic dermatitis, and allergic asthma in CF is probably equal to that of the normal population.
