chapter  3
chapter three
Pages 8

This protein is essential for allowing platelets to adhere to collagen as well as to one another.

• Once platelets have undergone the process of adhesion, substances such as thrombin, thromboxane A

and ADP lead to further platelet

activation

. Activated platelets now release the contents of their

internal granules, which include substances such as ADP, fibrinogen, thrombin, thromboxane A

and von Willebrand’s factor, which induce the

aggregation

of additional platelets at the injury site.