ABSTRACT
In addition to controlling the laboratory techniques involved in the study of postmortem brain neurobiology, it is also necessary to ensure the subjects from whom tissue is collected have an accurate psychiatric diagnosis. However, in a recent review of 60 major studies we showed that about half did not explain psychiatric diagnostic procedure and less than half specified the diagnostic criteria used (Keks et al., 1995a). There would thus seem to be a need to give more consideration to the validity of diagnosis on which neurobiological studies using postmortem tissue are based.
