ABSTRACT

First Published in 1994, Introduction to In Vitro Cytotoxicology examines in vitro cytotoxicology, which offers new methodologies to toxicity testing. This important new discipline of modern toxicology is gaining increased acceptance as a viable alternative to traditional testing methods. The text discusses the application of in vitro cytotoxicology to toxicity testing and human risk assessment, and it analyzes the advantages and limitations of the tests performed under scientific and regulatory conditions. The book also reviews the optimum utilization of certain tests for specific groups of chemicals relevant to validation programs currently in progress. This book is a useful reference tool for students, researchers, and practitioners interested in academic, industrial, and regulatory toxicology; environmental health; cell biology; pharmacology; dentistry; or human and veterinary medicine.

chapter Chapter 2|20 pages

Mechanisms of Cytotoxicology

chapter Chapter 3|12 pages

Cellular Methods of General Toxicity

chapter Chapter 4|30 pages

Cellular Methods of Target Organ Toxicity

chapter Chapter 5|12 pages

Cellular Methods of Local Toxicity

chapter Chapter 6|6 pages

Cellular Methods of Teratogenicity

chapter Chapter 7|14 pages

Cellular Methods of Immune Function

chapter Chapter 10|14 pages

Experimental Design and Statistics

chapter Chapter 11|20 pages

Standardization and Validation