chapter  Chapter 7
25 Pages

Brain Stimulation Therapies

WithBahman Zohuri, Patrick J. McDaniel

Brain stimulation therapies can play a role in treating certain mental disorders. Brain stimulation therapies involve activating or inhibiting the brain directly with electricity. This chapter reviews the understanding of the physiologic effects and presumed mechanism of effect of transcranial magnetic stimulation (TMS) as an antidepressant. Standard TMS procedure usually implies that the subject remains conscious and is comfortably sitting. The cap is worn during the stimulation that enables marking of the coil position on the surface of the head. Several methods for the localization of stimulation site can be applied regarding the region of interest. TMS is extensively used for investigation of the excitability of the human brain. Together, computational models of TES play a critical role in visualizing the electrical field distribution, understanding the mechanistic action of TES on neuronal network dynamics, and optimizing stimulation parameters to guide the design of the next generation of TES.