ABSTRACT
As craniofacial surgery has progressed, several initial problems have been solved while others remain, and still others are continually being discovered. There have been great demonstrations of wide mobilization of cranio-orbital bone segments to correct major deformity. However, excessively rigid fixation in infants or growing patients may be restrictive or deleterious to normal growth and development. The use of bone grafts, increasingly of membranous origin, has become more and more popular for filling defects, providing stronger support, and promoting better contour. However, its predictability with respect to remodeling and resorption is still quite inadequate. It was difficult to quantify hemorrhage or hemostasis but histologically, the bone wax and fibrin glue groups had much less hematoma formation than the control group. The fibrin glue group showed greater vascularity and more abundant bone growth than the bone wax group. The bone wax specimens displayed granuloma formation, hypocellularity, and actual necrosis of bone.
