ABSTRACT
111 A middle-aged large-breed dog presents as an emergency with acute onset of lethargy, pallor, and abdominal distension. Abdominal ultrasonography reveals a large amount of free abdominal fluid consistent with blood and a solitary mass on the patient’s spleen that measures at least 10 cm (~4") in diameter. The spleen is removed in an emergency surgery (Figure 111.1), and, following pRBC transfusion, the patient makes an uncomplicated recovery. There was no gross evidence of metastasis noted in any abdominal organs during surgery. https://s3-euw1-ap-pe-df-pch-content-public-p.s3.eu-west-1.amazonaws.com/9780429401725/9d69b4ae-80d1-4f44-9dcb-659cda134065/content/fig111_1_C.jpg"/>
i. What differential diagnoses are you considering for this splenic mass?
ii. If you are suspecting a neoplastic process, how would you plan to stage this patient?
iii. If this lesion were a hemangiosarcoma and you found no evidence of local or distant metastasis on further workup, what further adjunctive therapy, if any, would you recommend and why?
iv. Describe common sites for the development of hemangiosarcoma and the most likely sites for the development of distant metastasis.188
