ABSTRACT
Findings from low-dose radiation research suggest that the low-dose radiation effects are often different from medium- and high-dose radiation effects. Therefore, current focus on cancer and specific non-cancer radiation injuries from low-dose radiation may be insufficient. Moreover, because these endpoints were established through high-dose radiation studies, biological mechanisms that underlay them should be considered anew in low-dose radiation research. In addition, endpoints specific to low-dose radiation exposures may be possible to discover. Efforts to find them would be enriched through use of new animal models and widening of the repertoire of genetic mutations in these model systems. New biotechnology and modeling breakthroughs may provide rich support for such efforts.
