ABSTRACT

A Three-dimensional (3D) printing apparatus then forms the portions one layer at a time based on the two-dimensional (2D) slice information, stacking and assembling successive layers to create the ultimate 3D entity. In 3D printing, computer-aided design ­models of fragments to be constructed are initially sliced in an authentic environment to generate a stack of 2D parts. 3D printing allows for the ability to spatially configure cells and biomaterials in order to further closely review the structural, physical, chemical, and biological intricacy of tissues and organs, which has not been possible with other scaffold production technologies. The expression “3D biomaterial printing” refers to the physical extrusion of an “ink” that promptly stabilizes upon deposition through at all ranges of mechanisms and is repeated layer-by-layer to create a construct intended to cooperate with biology. Biomaterial inks must meet traditional biomaterial concerns in addition to 3D printing concerns.