ABSTRACT

Carbon tetrachloride (CCl4)-intoxicated rats showed significant elevation in serum enzymes, bilirubin, and lipid peroxidation and reduction in serum total protein, glutathione peroxidase, glutathione reductase, reduced glutathione, superoxide dismutase, and catalase activity. Treatment with ethanol extract of Eugenia floccosa leaf altered the above parameters to the levels of near normal. All the above results were comparable with the standard silymarin (100 mg/kg) treated group. Therefore, the present study establishes that the ethanol extract of Eugenia floccosa leaf possesses noteworthy hepatoprotective activity.