ABSTRACT
Male fertility is dependent on successful spermatogenesis to produce functional sperm in adequate quantities that are amenable to successful fertilization and subsequent embryogenesis. Spermatogenesis requires a series of spatially and temporally coordinated genetic, endocrine, and paracrine events. Numerous intrinsic and extrinsic factors can affect the efficiency of spermatogenesis and the fertilization potential of mature spermatozoa. This chapter provides an overview of spermatogenesis regulation, parameters regulating fertility, medical and environmental factors affecting fertility potential, and requirements for fertilization.
