ABSTRACT
Declining male infertility is a serious health concern faced in the present condition and on other hand, necessity for effective birth control measures by designing potent non hormonal contraceptives also increases. Our understanding of the molecular mechanisms underlying the impairment of spermatogenesis should be deepened and focused toward identification of potential protein targets that can be used as biomarkers as well for the design of therapeutic strategies. This chapter discusses the application of genomics, proteomics, and bioinformatics techniques that enhance the understanding of the molecular mechanisms of male infertility as well as identifies and evaluates the potential of genomic, miRNA, and protein targets that can be used as biomarkers for diagnosis and treatment of male infertility as well as for designing male contraceptives.
