ABSTRACT
Intravoxel incoherent motion diffusion-weighted imaging (IVIM DWI) is a noninvasive imaging method that probes the mobility of microscopic water molecules in biologic tissues and incorporates the contributions of microvascular perfusion and true cellular diffusion restriction. This method is well suited for investigation of focal liver lesions (FLL). Important technical considerations for IVIM include the selection of b values, acquisition technique, field strength, fitting algorithm, and postprocessing methods. Recent studies have explored the use of IVIM DWI for a variety of applications, including characterization of liver lesions, prediction of tumor grade, and 220evaluation of the post-treatment response. This chapter will discuss in detail the promising early results of IVIM assessment of FLL.
