ABSTRACT

A Probabilistic Model of the Genotype/Phenotype Relationship provides a new hypothesis on the relationship between genotype and phenotype. The main idea of the book is that this relationship is probabilistic, in other words, the genotype does not fully explain the phenotype. This idea is developed and discussed using the current knowledge on complex genetic diseases, phenotypic plasticity, canalization and others.

part 1|45 pages

The Genotype/Phenotype Relationship

chapter 1|7 pages

The Beginnings of Life

chapter 2|6 pages

Genetic Program and Self-Organization

chapter 3|4 pages

The Phenotype

chapter 4|7 pages

The Role of Genes

chapter 5|5 pages

The Share of the Environment

chapter 6|5 pages

Analogy Between Organisms and Particles

chapter 7|3 pages

Phenotypic Plasticity

chapter 8|6 pages

Behavior

part 2|45 pages

Heredity

chapter 9|5 pages

Reproduction and Phenotypic Canalization

chapter 10|6 pages

Fertilization and Overlapping of Genotypes

chapter 11|6 pages

Nature of Canalization

chapter 12|12 pages

Canalization: Experimental Data

chapter 13|10 pages

Implications of Canalization

chapter 14|4 pages

Canalization and Instinct

part 3|44 pages

Evolution

chapter 15|6 pages

Limits to Natural Selection

chapter 16|9 pages

Instinct and Evolution

chapter 17|10 pages

Biological Function

chapter 18|6 pages

Differentiation and Phenotypic Coherence

chapter 19|4 pages

Speciation

chapter 20|7 pages

Phenotypic Innovation