ABSTRACT
CH A P T E R 4 Constraint-based modelling of microbial communities
Constraint-based modelling comprises a collection of techniques, which have been commonly used to predict the metabolic phenotype of organisms at steady state. Organisms in nature confront different types of environments, harbouring different sets of resources. In order to survive, the organisms adapt by finetuning themselves to the exposed environments. Often, they tend to rewire their metabolism in response to the dynamic changes in the environment. The final phenotype must satisfy environmental constraints as well as other endogenous cellular constraints.
