ABSTRACT
Principles of Mucosal Immunology is designed for graduate students and postdoctoral fellows, researchers in immunology and microbiology, and medical and dental students. It presents the basic and clinical aspects of the mucosal immune system, focusing on the major components of the mucosal barrier the gastrointestinal, upper and lower respiratory,
I. Development and Structure of Mucosal Tissue 1. Overview of the Mucosal Immune System Structure2. Phylogeny of the Mucosal Immune System3. Immunological and Functional Differences Among Individual Compartments of the Mucosal Immune System4. Secreted Effectors of the Innate Mucosal BarrierII. Cellular Constituents of Mucosal Immune Systems and Their Function in Mucosal Homeostasis 5. Immune Function of Epithelial Cells6. Intraepithelial Lymphocytes: Unusual T Cells at Epithelial Surfaces7. Lymphocyte Populations within the Lamina Propria8. Mucosal B Cells and Their Function9. Secretory Immunoglobulins and Their Transport10. Role of Dendritic Cells in Integrating Immune Responses to Lumenal Antigens11. Intestinal Macrophages in Defense of the Mucosa12. Mucosal Basophils, Mast Cells, and Eosinophils13. M Cells and the Follicle-Associated Epithelium14. Lymphocyte Trafficking from Inductive Sites to Effector Sites15. Mucosal ToleranceIII. Microbial Commensalism 16. Recognition of Microbe-Associated Molecular Patterns by Pattern Recognition Receptors17. The Commensal Micorbiota and Its Relationship to Homeostasis and DiseaseIV. Genitourinary Tract 18. The Immune System of the Genitourinary Tract19. Mucosal Immune Responses to Microbes in the Genitourinary TractV. Nose, Airways, Oral Cavity, and Eyes 20. Immunobiology of the Nose, Upper Airways, and Oral Cavity21. Bronchial Associated Lymphoid Tissue and Immune-mediated Respiratory Diseases22. The Ocular Surface as a Mucosal Immune SiteVI. Infectious Diseases of Mucosal Surfaces 23. Mucosal Interactions with Enteropathogenic Bacteria24. Heliobacter pylori Infection25. Viral Infections26. Infection-driven Periodontal Disease27. Vaccine Strategies for Mucosal I
