ABSTRACT

Genetic Association Studies is designed for students of public health, epidemiology, and the health sciecnes, covering the main principles of molecular genetics, population genetics, medical genetics, epidemiology and statistics. It presents a balanced view of genetic associations with coverage of candidate gene studies as well as genome-wide association studies. All aspects of a genetic association study are included, from the lab to analysis and interpretation of results, but also bioinformatics approaches to causality assessment. The role of the environment in genetic disease is also highlighted. Genetic Association Studies will enable readers to understand and critique genetic association studies and set them on the way to designing, executing, analyzing, interpreting, and reporting their own.

 

 

 

 

chapter 1|24 pages

Primer on Molecular Genetics

chapter 2|16 pages

Primer on Medical Genetics

chapter 3|16 pages

Primer on Population Genetics

chapter 6|16 pages

Elementary Statistical Concepts

chapter 7|18 pages

Genotyping Methods and Errors