Name: Pharmaceutical Emulsions and Suspensions:Second Edition, Revised and Expanded
ISBN: 9780429344688

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ABSTRACT

Analyzes construction of experiments, focusing on variables, models, matrices, and reproducibility.
This timely reference systematically examines the basic concepts and theoretical issues, methodologies for experiment and measurement, and practical health applications of emulsions and dispersions-describing formulation problems and identifying potential carriers for the delivery or targeting of new drugs.
Evaluates anionic, cationic, and nonionic surfactants as dispersing, emulsifying, foaming, penetrating, and wetting agents.
Written by more than 20 international researchers, Pharmaceutical Emulsions and Suspensions

discusses uses of macroemulsions and (submicron) microemulsions

illuminates delivery devices such as microparticles, nanospheres, liposomes, and mixed micelles

investigates the application of self-emulsifying drug delivery systems (SEDDS)

introduces techniques for increasing drug solubility with nanosuspensions

addresses stabilization, flocculation, and coagulation problems in pharmaceutical and cosmetic suspensions

surveys drug delivery by way of dermatological, follicular, and ocular routes

explains the pharmacodynamics, bioavailability, and pharmacokinetics in the drug formulation development process

compares and contrasts monomeric and micellar adsorption at oil-water interfaces

and more!
Containing over 1800 references, tables, equations, drawings, and micrographs, Pharmaceutical Emulsions and Suspensions is an ideal resource for pharmacists; physical, surface, colloid, cosmetic, food, and agricultural chemists; and upper-level undergraduate and graduate students in these disciplines.

TABLE OF CONTENTS

Basic Concepts

Main Surfactants Used in the Pharmaceutical Field
Gilberte Marti-Mestres and Françoise Nielloud
Formulation Concepts for the Emulsion Maker
Jean-Louis Salager
Emulsion Properties and Related Know-how to Attain Them
Jean-Louis Salager
Suspensions Formulation
Fernando González-Caballero and Juan de Dios García López-Durán

Health Applications

Emulsions as Drug Delivery Systems
Katrin Buszello and Bernd W. Müller
Parenteral Fat Emulsions: Structure, Stability, and Applications
Jörn-Stefan Lucks, Bernd W. Müller, and Karsten Klütsch
The Use of Topical Emulsions as Drug Delivery Systems
Eric W. Smith, Christian Surber, and Howard I. Maibach
Vesicles as a Tool for Dermal and Transdermal Drug Delivery
J. A. Bouwstra
Ophthalmic Emulsions and Suspensions
M. Fabrizio Saettone, Boris Giannaccini, and Daniela Monti
Administration of Emulsions to the Gastrointestinal Tract
Duncan Q. M. Craig, Manisha J. Patel, and Marianne Ashford
Dry Adsorbed Emulsions
Michel Rollet and Jölle Bardon
Nanosuspensions for the Formulation of Poorly Soluble Drugs
R. H. Müller, C. Jacobs, and O. Kayser
Pharmaceutical Suspensions and Their Applications
V. Gallardo, M. A. Ruiz, and A. V. Delgado

Tools and Methods for Experiments and Measurements

Experimental Design in Emulsion and Suspension Formulations' Theocritical Aspects
Roger Phan-Tan-Luu and Didier Mathieu
Applications of Experimental Methodology to Emulsions and Suspensions
Françoise Nielloud, Gilberte Marti-Mestres, and Hélène Maillols
Rheology of Suspensions and Emulsions
Maria Isabel Briceño
Determination of Size Distributions of Sub-Micron Particle Dispersions by Photon Correlation Spectroscopy
E. R. Pike