ABSTRACT
Describes the state-of-the-art techniques and methods involved in the design, operation, preparation and containment of bioreactor systems, taking into account the interrelated effects of variables associated with both upstream and downstream stages of the design process. The importance of the initial steps in the development of a bioprocess, such
TABLE OF CONTENTS
chapter 2|34 pages
Organism Selection
Francisco Javier Castillo of products from biotechnology continue to be of microbial
chapter 3|42 pages
Bacterial, Yeast, and Fungal Cultures
Effect of Microorganism Type and Culture Characteristics on Bioreactor Design and Operation D. White
chapter 4|50 pages
Design, Formulation, and Optimization
of La Plata Ana Maria Giulietti of Buenos Aires
chapter 5|68 pages
Fundamentals of Bioreactor Design
Jose C. Merchuk* of the Negev Juan A. Asenjo of Chile
chapter 14|42 pages
Scale-Up
Carles Sola and Francese Godia Transferring to an industrial scale processes successfully developed at the lab-
chapter 15|36 pages
Sterilization and Containment
Andrew Sinclair and Michael H. J. Ashley I. INTRODUCTION
