ABSTRACT
Acute disseminated encephalomyelitis (ADEM) is an acute inflammatory demyelinating disorder of the CNS characterized by new onset focal or multifocal neurological signs and symptoms coupled with neuroimaging evidence of multifocal demyelinating lesions. ADEM (also referred to as post-or para-infectious encephalomyelitis) frequently follows a recognized prodromal infectious illness (most often viral) or antecedent event such as vaccination or immunization, administration of serum, or as an adverse reaction to drugs. ADEM typically follows a monophasic course.
