ABSTRACT

Inflammatory and immune-related ocular disorders encompass a wide spectrum of conditions. Electrophysiological testing may serve as a measure of retinal function in this group of diseases and has a critical diagnostic role in disorders such as paraneoplastic retinopathies. The topics covered in this chapter are:

Inflammatory retinal disorders:

Uveitis (non-specific intraocular inflammation) Presumed ocular histoplasmosis syndrome (POHS) and toxoplasmosis retinopathy

Behc¸et disease Vogt-Koyanagi-Harada disease Sympathetic ophthalmia Acute posterior multifocal placoid pigment epitheliopathy (APMPPE)

Serpiginous choroiditis

Birdshot retinochoroidopathy (vitiligenous chorioretinitis)

Diffuse unilateral subacute neuroretinitis (DUSN) Zonal inflammatory retinal disorders:

Acute zonal occult outer retinopathy (AZOOR) Multiple evanescent white-dot syndrome (MEWDS) Acute macular neuroretinopathy (AMN) Multifocal choroiditis Punctate inner choroidopathy (PIC)

Paraneoplastic and immune-related retinopathies:

Cancer-associated retinopathy (CAR) Recoverin-associated retinopathy and autoimmune retinopathy without cancer

Melanoma-associated retinopathy (MAR) CRMP-5 paraneoplastic retinopathy and optic neuropathy

INFLAMMATORY RETINAL DISORDERS

Uveitis (Non-Specific Intraocular Inflammation)

In acute iridocyclitis, or anterior uveitis, the ERG is normal because the retina is not involved (1).