ABSTRACT
Acknowledgments 42
References 42
1. INTRODUCTION
Agents that modulate healing such as the antimetabolites 5-fluorouracil (5FU) and
mitomycin-c (MMC) have revolutionized glaucoma surgery, in patients with a high risk
of surgical failure. There is increasing evidence from long-term prospective trials, that intra-
ocular pressures in the 10-15 mmHg range best preserve long-term vision in glaucoma
(1,2). However, vision threatening complications occur with the use of these agents (3,4).
