ABSTRACT

I. Introduction 397

II. Definitions 398

A. Lung Density 398

B. Lung Volumes 400

C. Lung Water and Blood Volume Measurements 402

D. Lung Ventilation and Perfusion 403

E. PA Pressures and Right Ventricular Function 405

F. Diffusion 409

III. Conclusion 410

References 411

I. Introduction

Every day, clinicians use imaging to diagnose disease and to assist in therapeutic

decision-making. The value of anatomic imaging of lung structure with X-ray

computed tomography (CT) is well known to every clinician. Advances in

molecular imaging that may eventually be used to guide gene therapy or to evalu-

ate biologic processes in vivo at the cellular and even subcellular levels hold

great promise. Recent improvements in instrumentation are making it possible

to combine different types of measurements into single multimodality imaging

sessions (see Chapter 7).