ABSTRACT
I. Introduction 594
II. Screening of Transplant Candidates 594
III. Complications in the Transplant Recipient 597
A. Reperfusion Pulmonary Edema/Primary Graft Failure 597 Radiographic Considerations 597
B. Airway Complications 598
Radiographic Considerations 599
C. Native Lung Hyperinflation 600
Radiographic Considerations 602
D. Infectious Complications 602
Radiographic Considerations 604
E. Post-transplant Lymphoproliferative Disease 606
Radiographic Considerations 607
F. Lung Cancer 607
Radiographic Considerations 608
G. Acute Allograft Rejection 609
Radiographic Considerations 609
H. Bronchiolitis Obliterans Syndrome 611
Radiographic Considerations 612
Acknowledgment 615
References 615
I. Introduction
Human lung transplantation was first attempted in 1963 but it was not until
two decades later that extended survival was achieved. Further refinements in
patient selection, surgical technique, immunosuppression, and post-operative
care have led to the successful application of lung transplantation to a wide
variety of advanced disorders of the airways, lung parenchyma, and pulmonary
vasculature (1). There has been a marked proliferation of lung transplant
centers worldwide and by the end of 2001, 14,000 procedures had been performed (2).