or microscopic disease, : of seven children died of distant metastatic disease (56). Nakayama et al. (54) of head and neck MFH which involved bone was of their treatment philosophy. They suggested that postoperative chemo-

doi:10.1201/b21609-73

ABSTRACT

Figure 22.7 (See color insert) Fibrosarcoma (100 magnification). Fibrosarcomas are composed of slender spindle-shaped cells oriented in interweaving bundles. This interlacing arrangement gives rise to the term herring-bone pattern and is associated with lower grade tumors. Nuclear pleormorphism is minimal.