ABSTRACT

Dissolution is becoming one of the most commonly automated functions in the modern pharmaceutical development and quality assurance (QA) laboratory. To the experienced dissolution analyst the reasons seem obvious. Dissolution methods are time-consuming and require a significant amount of labor. Beyond the cost of labor, the true cost of increased regulatory requirements and documentation can be better managed through automation. Additionally, the increased pressure to

deliver improved return to shareholders is driving various efficiency improvements relating to various aspects of pharmaceutical development and manufacturing, including dissolution analysis.