ABSTRACT
Jonathan Hutchinson is a convenient starting point for reviewing the history of
sarcoidosis (Table 1). In Hutchinson’s day, sarcoidosis was a curious skin illness of uncertain significance. With time, the disease gradually revealed its
multisystem manifestations. Advances in biochemistry, immunology, genetics,
and molecular technology have added new dimensions to our understanding of
complexity of sarcoidosis. Each addition to our knowledge increases our
curiosity, but the cause of sarcoidosis continues to elude us.
