ABSTRACT

Due to OSAS variability across patients, no precise protocol for CPAP titration exists, but general recommendations have been established. Usually, one starts at a low pressure of 4-5 cm, gradually increasing by 1-2 cm every 15-20minutes until the apneas, hypopneas, respiratory effort-related arousals, and snoring are abolished. Patients who hypoventilate or who have other comorbidities [e.g., chronic obstructive pulmonary disease, congestive heart failure (CHF)] may require in-line oxygen to correct hypoxia, generally only after obstructive events are controlled.