ABSTRACT
Polyisocyanates, a group of low-molecular-weight cross-linking agents, are the most commonly identified cause of occupational asthma (OA) worldwide (1-3). Polyisocyanates are generally synthesized by the reaction of amines or their hydrochlorides with phosgene, and are unique in their ability to catalyze the production of polyurethanea product of great cultural and commercial importance.
