ABSTRACT
Pulmonary hypertension is a frequent complication of chronic obstructive pulmonary
disease (COPD). Its presence is associated with shorter survival, more frequent
exacerbation episodes, and greater need of health resources. At present, there is no
specific and effective treatment for this condition in COPD. However, recent advances
in the understanding of the pathobiology of pulmonary hypertensive states, along with
the development of effective treatments for pulmonary arterial hypertension, have
opened a new perspective that might be relevant in COPD.