ABSTRACT
The effects of solvents and vehicles on the skin are important since skin is the largest
organ of the human body and provides protection against the external environment.
In addition, the skin enables us to maintain a state of homeostasis. However, skin
and its barrier properties may be altered when exposed to various chemical agents.
Exposure to solvents and vehicles can occur after occupational or accidental
spillage, topical application of cosmetics, sunscreens, insect repellents, as well as
following the topical application of drugs for therapeutic purposes.