ABSTRACT
This book is the first to provide both a broad overview of the current methodologies being applied to drug design and in-depth analyses of progress in specific fields. It details state-of-the-art approaches to pharmaceutical development currently used by some of the world's foremost laboratories. The book features contributors from a variety of fields, new techniques, previously unpublished data, and extensive reference lists.
TABLE OF CONTENTS
section Section I|158 pages
Chemical Approaches to Rational Drug Design
chapter Chapter 1|32 pages
Design, Synthesis, and Antitumor Activity of an Inhibitor of Ribonucleotide Reductase
chapter Chapter 2|27 pages
The Development of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Inhibitors
chapter Chapter 3|21 pages
The Development of Potent Angiotensin II Receptor Antagonists Using a Novel Peptide Pharmacophore Model
section Section II|103 pages
Structural Approaches to Rational Drug Design